Expression of cyclo-oxygenase-2 in human atherosclerotic carotid arteries.

  title={Expression of cyclo-oxygenase-2 in human atherosclerotic carotid arteries.},
  author={Veronika Stemme and Jesper Swedenborg and H E Cla{\'e}sson and G{\"o}ran K. Hansson},
  journal={European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery},
  volume={20 2},
OBJECTIVES the preventive effect of acetylsalicylic acid in cardiovascular disease may be due to inhibition of platelet aggregation mediated by COX-1, but may in addition be due to anti-inflammatory effects by inhibition of COX-2. The objective of this study was to analyse the expression of COX-1 and COX-2 in atherosclerotic and healthy vascular walls. DESIGN the expression COX-1 and COX-2 was analysed in biopsies from human atherosclerotic carotid arteries and from healthy mammary arteries… CONTINUE READING


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