Expression of cyclins A, D2 and D3 in individual normal mitogen stimulated lymphocytes and in MOLT-4 leukemic cells analyzed by multiparameter flow cytometry.

@article{Gong1995ExpressionOC,
  title={Expression of cyclins A, D2 and D3 in individual normal mitogen stimulated lymphocytes and in MOLT-4 leukemic cells analyzed by multiparameter flow cytometry.},
  author={Jian-ping Gong and Umesh Bhatia and Frank Traganos and Zbigniew Darzynkiewicz},
  journal={Leukemia},
  year={1995},
  volume={9 5},
  pages={893-9}
}
Cyclins are regulatory subunits of the cyclin dependent kinases (CDKs), the enzymes that drive the cell through the respective phases and check-points of the cell cycle. The expression of cyclins in non-tumor cells, regulated by timely induction of their synthesis and proteolysis, is scheduled, occurring at discrete periods of the cell cycle. Using… CONTINUE READING