Expression of connexin genes in hippocampus of kainate-treated and kindled rats under conditions of experimental epilepsy.

@article{Shl2000ExpressionOC,
  title={Expression of connexin genes in hippocampus of kainate-treated and kindled rats under conditions of experimental epilepsy.},
  author={Goran S{\"o}hl and Martin Gueldenagel and Heinz Beck and Barbara Teubner and Otto Traub and Rafael Gutierrez and Uwe F Heinemann and Klaus Willecke},
  journal={Brain research. Molecular brain research},
  year={2000},
  volume={83 1-2},
  pages={44-51}
}
We have analyzed whether the expression of connexin genes is altered in the hippocampus of kindled and kainate-treated rats, i.e., animal models of human temporal lobe epilepsy. We have tested this hypothesis by analyzing mRNA, protein abundance and cellular location of connexins (Cx) 43, 36, 32 and 30. The expression of glial fibrillary acid protein and mRNA was also monitored both in kainate-treated and kindled rats, in order to take into account reactive gliosis under these conditions. We… CONTINUE READING

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