Expression of collagenolytic/gelatinolytic metalloproteinases by normal cornea.

  title={Expression of collagenolytic/gelatinolytic metalloproteinases by normal cornea.},
  author={Mary Elizabeth Fini and M T Girard},
  journal={Investigative ophthalmology & visual science},
  volume={31 9},
Members of the gelatinase subclass of the matrix metalloproteinase family have the capacity to degrade denatured collagens of all types and native types IV, V, and VII collagens. The authors identified the metalloproteinase species of the gelatinase class produced by the cells of rabbit corneal tissue. Two different molecular forms of gelatinase, visualized as enzymatic activities, that undergo electrophoresis with different mobilities on gelatin zymograms are synthesized by corneal cells in… CONTINUE READING
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