Expression of class II antigen in endotoxin induced uveitis.

  title={Expression of class II antigen in endotoxin induced uveitis.},
  author={Min Kyoung Kim and Alan Gary Palestine and Robert B. Nussenblatt and Chi Chao Chan},
  journal={Current eye research},
  volume={5 11},
Uveitis can be induced by systemic or intravitreal administration of endotoxin (lipopolysaccharide, LPS). In this study we correlated the expression of class II antigens (la in rat) of the Major Histocompatibility Complex (MHC), with this experimental model of uveitis. Ia antigen was detected by immunohistochemistry using the Avidin-Biotin-Peroxidase Complex (ABC) method and the monoclonal antibody OX6. Ia antigen was not expressed in normal eyes. However, Ia was expressed in the anterior uvea… CONTINUE READING


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