Expression of class I histone deacetylases (HDAC1 and HDAC2) in oesophageal adenocarcinomas: an immunohistochemical study.

Abstract

BACKGROUND Histone deacetylases (HDACs) are enzymes which play a central role in post-translational histone and non-histone protein modification. Deregulation of HDACs has been detected in various human malignancies and may also influence response to chemotherapy. AIMS To investigate the expression of class I histone deacetylase (HDAC) isoforms 1 and 2 in… (More)
DOI: 10.1136/jcp.2010.080952

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