Expression of chondro-osteogenic BMPs in ossified failed tendon healing model of tendinopathy.

  title={Expression of chondro-osteogenic BMPs in ossified failed tendon healing model of tendinopathy.},
  author={Pauline Po Yee Lui and Yin Mei Wong and Yun Feng Rui and Yuk Wa Lee and Lai Shan Chan and Kai-ming Chan},
  journal={Journal of orthopaedic research : official publication of the Orthopaedic Research Society},
  volume={29 6},
Chondrocytes phenotype/markers were expressed in clinical samples of tendinopathy and calcifying tendinopathy. This study examined the spatial-temporal expression of chondro-osteogenic Bone Morphogenetic Proteins (BMPs), which might contribute to ectopic chondro-osteogenesis and failed healing process in tendinopathy. Collagenase was injected into patellar tendon of rats to induce ossified failed tendon healing. At week 2, 4, 8, 12, and 16, the patella tendon was harvested for… CONTINUE READING
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