Expression of cell adhesion molecules in dilated cardiomyopathy: evidence for endothelial activation in inflammatory cardiomyopathy.

@article{Noutsias1999ExpressionOC,
  title={Expression of cell adhesion molecules in dilated cardiomyopathy: evidence for endothelial activation in inflammatory cardiomyopathy.},
  author={Michel Noutsias and Bettina Seeberg and Heinz Peter Schultheiss and Uwe K{\"u}hl},
  journal={Circulation},
  year={1999},
  volume={99 16},
  pages={2124-31}
}
BACKGROUND Dilated cardiomyopathy (DCM) is pathogenically linked to inflammatory cardiomyopathy (InfCM), which is characterized by intramyocardial infiltration. The transendothelial migration of immunocompetent cells is mediated by cell adhesion molecules (CAMs). METHODS AND RESULTS We investigated the expression pattern of CAMs (immunoglobulin superfamily, 32 selectins, and beta1- and beta2-integrins) in endomyocardial biopsies from DCM patients (n=152; left ventricular ejection fraction <40… CONTINUE READING

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