Expression of caveolin-1 is correlated with Akt-1 in colorectal cancer tissues.

@article{Kim2006ExpressionOC,
  title={Expression of caveolin-1 is correlated with Akt-1 in colorectal cancer tissues.},
  author={Hyun Ah Kim and Kwang-Ho Kim and R D Lee},
  journal={Experimental and molecular pathology},
  year={2006},
  volume={80 2},
  pages={165-70}
}
Caveolin is a major component of caveolae which is a plasma membrane microdomain. The emerging role of caveolin in tumorigenesis was based mainly on in vitro experiments with cancer cell lines. We performed semi-quantitative RT-PCR for caveolin, Akt and EGFR to understand the role of caveolins in colorectal tumor biology. Cancer tissue samples and the neighboring normal colon mucosa were obtained from 95 colorectal cancer patients who underwent operations at Ewha Womans University Mokdong… CONTINUE READING
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