Expression of cathepsin L and its inhibitor hurpin in inflammatory and neoplastic skin diseases

@article{Bylait2006ExpressionOC,
  title={Expression of cathepsin L and its inhibitor hurpin in inflammatory and neoplastic skin diseases},
  author={Matilda Bylaitė and Hayat Moussali and Irena Mar{\vc}iukaitienė and Thomas Ruzicka and Markus Walz},
  journal={Experimental Dermatology},
  year={2006},
  volume={15}
}
Abstract:  Cathepsin (Cat) L is an important lysosomal proteinase involved in a variety of cellular functions including intracellular protein turnover, epidermal homeostasis and hair development. Hurpin (serpinB13) is a cross‐class specific serine protease inhibitor of Cat L. We have analysed the expression and localization of Cat L and hurpin in various inflammatory and neoplastic diseases by immunohistochemistry. Whereas Cat L expression in normal skin was below detection limit… Expand
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