Expression of canine distemper virus receptor nectin-4 in the central nervous system of dogs

Abstract

Canine distemper virus (CDV) exhibits lymphotropic, epitheliotropic, and neurotropic nature, and causes a severe systemic infection in susceptible animals. Initially, signaling lymphocyte activation molecule (SLAM) expressed on immune cells has been identified as a crucial cellular receptor for CDV. Currently, nectin-4 expressed in epithelia has been shown… (More)
DOI: 10.1038/s41598-017-00375-6

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