Expression of cancer-testis genes in brain tumors.

  title={Expression of cancer-testis genes in brain tumors.},
  author={Myoung-Hee Lee and E I Son and Ealmaan Kim and In-Soo Kim and Man-Bin Yim and Sang-Pyo Kim},
  journal={Journal of Korean Neurosurgical Society},
  volume={43 4},
OBJECTIVE Cancer-testis (CT) genes are considered promising candidates for immunotherapeutic approaches. The aim of this study was to investigate which CT genes should be targeted in immunotherapy for brain tumors. METHODS We investigated the expression of 6 CT genes (MAGE-E1, SOX-6, SCP-1, SSX-2, SSX-4, and HOM-TES-85) using reverse-transcription polymerase chain reaction in 26 meningiomas and 32 other various brain tumor specimens, obtained from the patients during tumor surgery from 2000… CONTINUE READING


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