Expression of calcitonin gene-related peptide in anterior and posterior horns of the spinal cord after brachial plexus injury

@article{Chen2010ExpressionOC,
  title={Expression of calcitonin gene-related peptide in anterior and posterior horns of the spinal cord after brachial plexus injury},
  author={Long-Ju Chen and Fu Zhang and Jing Li and Hong-Xian Song and Li-Bing Zhou and B C Yao and Feng Li and Wenchun Li},
  journal={Journal of Clinical Neuroscience},
  year={2010},
  volume={17},
  pages={87-91}
}

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References

SHOWING 1-10 OF 19 REFERENCES

Gestational Changes in Calcitonin Gene-Related Peptide, Nerve Growth Factor, and Its Receptors in Rat Dorsal Root Ganglia1

TLDR
It is hypothesized that increased levels of ovarian hormones during pregnancy may elevate the synthesis of CGRP and NGF receptors in the DRG, and postpartum decreases in C GRP synthesis appear to be unrelated to NGF and its receptors.

Effects of calcitonin gene-related peptide on the expression and activity of nitric oxide synthase during mandibular bone healing in rabbits: an experimental study.

Glial cell line‐derived neurotrophic factor increases calcitonin gene‐related peptide immunoreactivity in sensory and motoneurons in vivo

TLDR
The GDNF treatment not only increased CGRP immunoreactivity in both sensory and motoneurons but also resulted in hypertrophy of both populations, reasoning that at least some of the regenerative effects of GDNF are mediated through C GRP up‐regulation.