Expression of cadherin-8 in renal cell carcinoma and fetal kidney.

  title={Expression of cadherin-8 in renal cell carcinoma and fetal kidney.},
  author={Sabine Blaschke and Claudia Anna M{\"u}ller and Jasmina Z Markovi{\'c}-Lipkovski and Sabine Puch and Nicolai Miosge and Volker Becker and Gerhard A. M{\"u}ller and Gerd Klein},
  journal={International journal of cancer},
  volume={101 4},
Cadherins represent a family of calcium-dependent cell adhesion molecules with an important regulatory function for maintenance of tissue architecture. Alterations of cadherin expression have been demonstrated in the development and progression of different epithelial tumors. In renal cell carcinoma (RCC), the majority of tumors express N-cadherin and cadherin-6. Screening a series of 16 RCC cell lines for the expression of different novel type II cadherins by RT-PCR revealed a complex pattern… CONTINUE READING