Expression of cadherin 23 isoforms is not conserved: implications for a mouse model of Usher syndrome type 1D


PURPOSE We compared cadherin 23 (Cdh23) mRNA and protein variants in the inner ear and retina of wild-type and mutant mice and primates to better understand the pleiotropic effects of Cdh23 mutations, and specifically to understand the absence of retinal degeneration in Cdh23 mutant mice. METHODS Semiquantitative real-time PCR was used to compare the… (More)


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