Expression of c-ret promotes morphogenesis and cell survival in mIMCD-3 cells.

Abstract

c-Ret, a protein tyrosine kinase receptor, and its ligand glial-derived neurotropic factor (GDNF) are critical for early regulation of ureteric bud development and nephrogenesis. To address whether c-ret directly initiates epithelial cell morphogenesis, the c-ret receptor was expressed in murine inner medullary collecting duct cells (mIMCD-3, a cell line of… (More)
DOI: 10.1152/ajprenal.1999.276.4.F581

Topics

8 Figures and Tables

Slides referencing similar topics