Expression of c-Myc, c-Fos, and c-jun in hepatocellular carcinoma.

@article{Yuen2001ExpressionOC,
  title={Expression of c-Myc, c-Fos, and c-jun in hepatocellular carcinoma.},
  author={Man Fung Yuen and P. C. Wu and V C Lai and Johnson Y. N. Lau and Ching Lung Lai},
  journal={Cancer},
  year={2001},
  volume={91 1},
  pages={106-12}
}
BACKGROUND Increased expression of the proto-oncogene c-myc is a common phenomenon in hepatocellular carcinoma (HCC). The proto-oncogenes c-fos and c-jun are involved in cell cycle progression and cellular proliferation. METHODS The objective of this study was to elucidate the mechanism of hepatocarcinogenesis with regard to the expressions of c-myc, c-fos, and c-jun. One hundred fifty biopsied HCC specimens were stained immunohistochemically for the above phenotypic markers both in tumor… CONTINUE READING

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