Expression of brain natriuretic peptide gene in human heart. Production in the ventricle.

@article{Hosoda1991ExpressionOB,
  title={Expression of brain natriuretic peptide gene in human heart. Production in the ventricle.},
  author={Kiminori Hosoda and K. Nakao and Masashi Mukoyama and Yuki Saito and Michihisa Jougasaki and Gotaro Shirakami and Sadao Suga and Yoshihiro Ogawa and Hirofumi Yasue and Hiroo Imura},
  journal={Hypertension},
  year={1991},
  volume={17 6 Pt 2},
  pages={1152-5}
}
To elucidate the expression of the brain natriuretic peptide gene in the human heart, we have measured brain natriuretic peptide mRNA levels in hearts using the Northern blot hybridization method. Brain natriuretic peptide mRNA was present with a size of approximately 0.9 kb in the ventricle as well as in the atrium. The brain natriuretic peptide mRNA level in the ventricle was 52% of that in the atrium, whereas the atrial natriuretic peptide mRNA level in the ventricle was approximately two… CONTINUE READING

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