Expression of beta-defensin genes in bovine alveolar macrophages.

@article{Ryan1998ExpressionOB,
  title={Expression of beta-defensin genes in bovine alveolar macrophages.},
  author={Lisa Kathleen Ryan and Janice Rhodes and Meenakshi Bhat and Gill Diamond},
  journal={Infection and immunity},
  year={1998},
  volume={66 2},
  pages={
          878-81
        }
}
Bovine alveolar macrophages (BAM) were examined for the expression of beta-defensins and to determine whether their expression could be upregulated by bacterial lipopolysaccharide (LPS), as observed with beta-defensins expressed in bovine tracheal epithelial cells. Four beta-defensins were expressed constitutively in BAM, with bovine neutrophil beta-defensin (BNBD)-4 and BNBD-5 being the most predominant. This is the first evidence of beta-defensin gene expression in a mature myeloid cell. LPS… CONTINUE READING

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