Expression of bcl-6 and CD10 protein is associated with longer overall survival and time to treatment failure in follicular lymphoma.

@article{Bilalovi2004ExpressionOB,
  title={Expression of bcl-6 and CD10 protein is associated with longer overall survival and time to treatment failure in follicular lymphoma.},
  author={Nurija Bilalovi{\'c} and Anne Kirsti Blystad and Rastko Golouh and Jahn Martin Nesland and Ivan Selak and Don Trinh and Emina Emilia Torlakovic},
  journal={American journal of clinical pathology},
  year={2004},
  volume={121 1},
  pages={34-42}
}
Follicular lymphomas (FLs) are a heterogeneous group of tumors, but prognostic factors are evaluated insufficiently in this common hematologic neoplasm. While bcl-6 and CD10 are expressed characteristically in FLs, their significance for biologic behavior of FL has not been studied previously. Samples from 73 patients with FL and clinical follow-up from 7 to 231 months were evaluated by immunohistochemical analysis. Patients with high levels of bcl-6 expression had favorable overall survival… CONTINUE READING