Expression of bacterial cysteine biosynthesis genes in transgenic mice and sheep: toward a newin vivo amino acid biosynthesis pathway and improved wool growth

@article{Bawden1995ExpressionOB,
  title={Expression of bacterial cysteine biosynthesis genes in transgenic mice and sheep: toward a newin vivo amino acid biosynthesis pathway and improved wool growth},
  author={C Simon Bawden and Arapaut V. Sivaprasad and Paul John Verma and Simon K. Walker and George Ernest Rogers},
  journal={Transgenic Research},
  year={1995},
  volume={4},
  pages={87-104}
}
It is possible to improve wool growth through increasing the supply of cysteine available for protein synthesis and cell division in the wool follicle. As mammals can only synthesis cysteine indirectly from methionine via trans-sulphuration, expression of transgenes encoding microbial cysteine biosynthesis enzymes could provide a more efficient pathway to cysteine synthesis in the sheep. If expressed in the rumen epithelium, the abundant sulphide, produced by ruminal microorganisms and normally… CONTINUE READING
9 Citations
63 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 63 references

Genetic analysis

  • H. Cherest, Y. Surdin-Kerjan
  • 1992

Germ line manipulation : application in agriculture and biotechnology

  • A. J. Clark, J. P. Simons, I. Wilmut
  • 1992

Expression of microbial cysteine biosynthesis genes in sheep by transgenesis

  • C. S. Bawden
  • Ph .D. thesis
  • 1991
3 Excerpts

Similar Papers

Loading similar papers…