Expression of aromatase cytochrome P-450 in premenopausal and postmenopausal human ovaries: an immunocytochemical study.

@article{Inkster1991ExpressionOA,
  title={Expression of aromatase cytochrome P-450 in premenopausal and postmenopausal human ovaries: an immunocytochemical study.},
  author={S. E. Inkster and Angela M. H. Brodie},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1991},
  volume={73 4},
  pages={717-26}
}
The cellular distribution of the aromatase cytochrome P-450 enzyme in human ovaries has been investigated immunocytochemically, using an aromatase-specific monoclonal antibody. Ovaries of females ranging in age from prepubertal infant girl through to postmenopausal adulthood were obtained from immediate autopsy or after surgery. The results have revealed temporal and spatial changes in expression of aromatase at different stages of development. No immunoreactive aromatase was detected in the… CONTINUE READING
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