Expression of aromatase and two isozymes of 5α-reductase in the developing green anole forebrain.

@article{Cohen2012ExpressionOA,
  title={Expression of aromatase and two isozymes of 5α-reductase in the developing green anole forebrain.},
  author={Rachel E. Cohen and Juli Wade},
  journal={Journal of neuroendocrinology},
  year={2012},
  volume={24 9},
  pages={1213-21}
}
Neural steroids, as well as the enzymes that produce these hormones, are important for sexual differentiation of the brain during development. Aromatase converts testosterone into oestradiol. 5α-reductase converts testosterone to 5α-dihydrotestosterone and occurs in two isozymes: type 1 (5αR1) and type 2 (5αR2). Each of these enzymes is present in the… CONTINUE READING