Expression of apoptosis regulatory proteins in tubular epithelium stressed in culture or following acute renal failure.

@article{Ortiz2000ExpressionOA,
  title={Expression of apoptosis regulatory proteins in tubular epithelium stressed in culture or following acute renal failure.},
  author={Alberto Ortiz and Corina Lorz and Marina Pen{\'e}lope Catalan and Theodore M. Danoff and Yoshiki Yamasaki and Jes{\'u}s Egido and Eric G. Neilson},
  journal={Kidney international},
  year={2000},
  volume={57 3},
  pages={969-81}
}
BACKGROUND While tubular cell death is a characteristic of acute renal failure (ARF), the molecular mechanisms that modulate this cell death are unclear. Cell fate in acute renal failure hinges on a balance of survival and mortality factors in a changing environment. We further explored this issue by studying selected cell death-related proteins in experimental renal failure. METHOD The expression of genes that promote (c-myc, Bax, BclxS) or protect (Bcl2, BclxL) from cell death was studied… CONTINUE READING

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