Expression of apoptosis and cell cycle related genes in proliferating and colcemid arrested cells of divergent lineage.

@article{Gallaher2000ExpressionOA,
  title={Expression of apoptosis and cell cycle related genes in proliferating and colcemid arrested cells of divergent lineage.},
  author={B. W. Gallaher and Antje Berthold and J{\"u}rgen Klammt and Matthias Knuepfer and J{\"u}rgen Kratzsch Kratzsch and Michael Bartsch and Wieland Kiess},
  journal={Cellular and molecular biology},
  year={2000},
  volume={46 1},
  pages={79-88}
}
Progression through the cell cycle and redirection of cells towards programmed cell death (apoptosis) are tightly inter-related processes. However the requirement for tissue and cell type specificity suggests that a wide variety of mechanisms are used to achieve the same purpose. To examine this issue, we investigated cell cycle (c-myc, p53, p21/WAF) and apoptosis related (bcl-2, bcl-X(L), bax-alpha) gene expression in two cell lines of very different origin under proliferating and apoptosis… CONTINUE READING