Expression of apolipoprotein A-I in porcine brain endothelium in vitro.

@article{Mckel1994ExpressionOA,
  title={Expression of apolipoprotein A-I in porcine brain endothelium in vitro.},
  author={Bettina M{\"o}ckel and Heike Zinke and Robert B. Flach and Bertram K. Wei\ss and H Weiler-G{\"u}ttler and Hans G{\"u}nter Gassen},
  journal={Journal of neurochemistry},
  year={1994},
  volume={62 2},
  pages={788-98}
}
Apolipoprotein (apo) A-I is the major protein component of high-density lipoproteins (HDLs), which are responsible for reverse cholesterol transport from peripheral tissues to the liver. A low level of plasma HDL is correlated with susceptibility to atherosclerosis and coronary heart disease. Mammalian apo A-I synthesis has been attributed mainly to liver and intestine. Recently, apo A-I expression has been shown in porcine brain capillaries, suggesting an independent lipid metabolism within… CONTINUE READING