Expression of anion exchangers in cultured human endolymphatic sac epithelia.


HYPOTHESIS Pendrin acts as a Cl-/HCO3- exchanger and is responsible for endolymphatic fluid volume and pH homeostasis in human endolymphatic sac epithelial cells. BACKGROUND The endolymphatic sac (ES) is part of the membranous labyrinth in the inner ear that plays an important role in maintaining homeostasis of the endolymphatic fluid system. However, the… (More)
DOI: 10.1097/MAO.0b013e31826bf3d3