Expression of an early myelopoietic antigen (CD33) on a subset of human umbilical cord blood-derived natural killer cells.

@article{Handgretinger1993ExpressionOA,
  title={Expression of an early myelopoietic antigen (CD33) on a subset of human umbilical cord blood-derived natural killer cells.},
  author={Rupert Handgretinger and Holger Sch{\"a}fer and François Baur and Daniel S Frank and C Ottenlinger and Hans J{\"o}rg B{\"u}hring and Dietrich Niethammer},
  journal={Immunology letters},
  year={1993},
  volume={37 2-3},
  pages={223-8}
}
A new subset of natural killer (NK) cells was identified in human umbilical cord blood. This subset of CD56+/CD3- NK cells co-expressed the CD33 antigen, which is present on early hematopoietic progenitors confined to the myeloid lineage. The percentage of the CD56+/CD33+ cells among the CD56+/CD3- NK cells was 7.9 +/- 6.6% (n = 27) with a range of 1.4-25.5% and a considerable individual variability. Additionally, the majority of freshly isolated CD56+/CD33+ cells co-expressed the CD2 and CD7… CONTINUE READING

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