Expression of an NK2 homeodomain gene in the apical ectoderm defines a new territory in the early sea urchin embryo.

@article{Takacs2004ExpressionOA,
  title={Expression of an NK2 homeodomain gene in the apical ectoderm defines a new territory in the early sea urchin embryo.},
  author={Carter M. Takacs and Gabriele Amore and Paola Oliveri and Albert J. Poustka and Diana Wang and Robert D. Burke and Kevin Jacob Peterson},
  journal={Developmental biology},
  year={2004},
  volume={269 1},
  pages={
          152-64
        }
}
We have identified an NK2 family homeodomain transcription factor, SpNK2.1, in the sea urchin Strongylocentrotus purpuratus whose transcripts are initially detected within the apical plate ectoderm of the hatching blastula and are confined to the apical organ at least through 2 weeks of development. Protein localization studies demonstrate that SpNK2.1 is restricted to the apical plate epithelium, but is excluded from the nucleus of serotonergic neurons. The expression profile of SpNK2.1 is… CONTINUE READING
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