Expression of alkaline phosphatase loci in mammalian tissues.

  title={Expression of alkaline phosphatase loci in mammalian tissues.},
  author={David John Goldstein and Clare Rogers and Harry Harris},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={77 5},
Alkaline phosphatases [orthophosphoric-monoester phosphohydrolase (alkaline optimum), EC] have been examined in liver, bone, kidney, intestine, and placenta from nine mammalian species by quantitative inhibition and thermostability studies and compared with alkaline phosphatases in the corresponding human tissues. In humans, three kinds of alkaline phosphatase can be sharply differentiated by these methods, one occurring in liver, bone, and kidney, one in intestine, and one in placenta… CONTINUE READING


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