Expression of acyl-CoA synthetase 5 reflects the state of villus architecture in human small intestine.

@article{Gassler2004ExpressionOA,
  title={Expression of acyl-CoA synthetase 5 reflects the state of villus architecture in human small intestine.},
  author={Nikolaus Gassler and J{\"u}rgen Kopitz and Arman Tehrani and Birgit Ottenw{\"a}lder and Martina Schnoelzer and Juergen Kartenbeck and Stefan Lyer and Frank Autschbach and Annemarie Poustka and Herwart F. Otto and Jan Mollenhauer},
  journal={The Journal of pathology},
  year={2004},
  volume={202 2},
  pages={188-96}
}
Several disorders of the small intestine are associated with disturbances in villus architecture. Thus, an understanding of the molecular mechanisms associated with the differentiation of villi represents an important step in the improvement of the understanding of small intestinal pathology. Screening of antibodies from a hybridoma library led to the identification of an acyl-CoA synthetase 5-specific monoclonal antibody. Protein synthesis, mRNA expression, and the enzyme activity of acyl-CoA… CONTINUE READING