Expression of a whey acidic protein transgene during mammary development. Evidence for different mechanisms of regulation during pregnancy and lactation.

Abstract

Expression of the mouse whey acidic protein (WAP) gene is specific to the mammary gland, is induced several thousand-fold during pregnancy, and is under the control of steroid and peptide hormones. To study developmental regulation of the mouse WAP gene, a 7.2-kilobase (kb) WAP transgene, including 2.6 kb of 5'- and 1.6 kb of 3'-flanking sequences, was… (More)

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@article{Burdon1991ExpressionOA, title={Expression of a whey acidic protein transgene during mammary development. Evidence for different mechanisms of regulation during pregnancy and lactation.}, author={T. A. Burdon and Lakshmanan Sankaran and R J Wall and Michael W. Spencer and Lothar Hennighausen}, journal={The Journal of biological chemistry}, year={1991}, volume={266 11}, pages={6909-14} }