Expression of a uniquely regulated extracellular polysaccharide confers a large-capsule phenotype to Bacteroides fragilis.

  title={Expression of a uniquely regulated extracellular polysaccharide confers a large-capsule phenotype to Bacteroides fragilis.},
  author={Maria Chatzidaki-Livanis and M. Coyne and Hazeline Roche-Hakansson and L. Comstock},
  journal={Journal of bacteriology},
  volume={190 3},
  • Maria Chatzidaki-Livanis, M. Coyne, +1 author L. Comstock
  • Published 2008
  • Biology, Medicine
  • Journal of bacteriology
  • Bacteroides fragilis synthesizes eight distinct capsular polysaccharides, more than any described bacterium outside the order Bacteroidales. Here, we show that this organism also produces a high-molecular-weight extracellular polysaccharide (EPS). Expression of the EPS results in the formation of a large polysaccharide layer around the bacteria which prevents them from forming a tight pellet upon centrifugation and from entering a Percoll density gradient. Like expression of the capsular… CONTINUE READING
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