Expression of a novel splice variant of human mGluR1 in the cerebellum
@article{Makoff1997ExpressionOA, title={Expression of a novel splice variant of human mGluR1 in the cerebellum}, author={Andrew J. Makoff and T. Phillips and C Pilling and Piers C. Emson}, journal={NeuroReport}, year={1997}, volume={8}, pages={2943–2947} }
WE have isolated clones of a novel splice variant of metabotropic glutamate receptor type 1 (mGluR1) from a human cerebellum cDNA library. Translation of this variant, mGluR1g would result in the addition of just one amino acid after the exon/intron boundary where the other splice variants diverge. RNA dot blot analysis using an mGluR1g-specific probe demonstrated expression in the cerebellum and also high levels in the kidney. Northern blotting using the same probe showed expression of a 4 κB…
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