Expression of a liver fatty acid binding protein/human decay-accelerating factor/HLA-B44 chimeric gene in transgenic mice.

@article{Hansbrough1991ExpressionOA,
  title={Expression of a liver fatty acid binding protein/human decay-accelerating factor/HLA-B44 chimeric gene in transgenic mice.},
  author={J R Hansbrough and Douglas M. Lublin and Kevin A. Roth and Edward Birkenmeier and J. I. Gordon},
  journal={The American journal of physiology},
  year={1991},
  volume={260 6 Pt 1},
  pages={G929-39}
}
The intestinal epithelium is characterized by the rapid and continuous renewal of its four principal cell types and by its ability to establish and maintain remarkably complex spatial differentiation along its crypt-to-villus and duodenal-to-colonic axes. We have previously used transgenic mice containing liver fatty acid binding protein/human growth hormone (L-FABP/hGH) fusion genes to analyze the molecular mechanisms responsible for encoding positional information in this epithelium. Because… CONTINUE READING