Expression of a highly conserved oncofetal gene, TA1/E16, in human colon carcinoma and other primary cancers: homology to Schistosoma mansoni amino acid permease and Caenorhabditis elegans gene products.

@article{Wolf1996ExpressionOA,
  title={Expression of a highly conserved oncofetal gene, TA1/E16, in human colon carcinoma and other primary cancers: homology to Schistosoma mansoni amino acid permease and Caenorhabditis elegans gene products.},
  author={Dr. A.-M. Wolf and Song Wang and M A Panzica and N H Bassily and Nancy L. Thompson},
  journal={Cancer research},
  year={1996},
  volume={56 21},
  pages={5012-22}
}
The peptides encoded by the rat liver oncofetal cDNA TA1 and the human lymphocyte activation gene E16 display a high degree of homology with coding regions recently identified in Schistosoma mansoni and Caenorhabditis elegans. Previous studies showed that up-regulation of TA1/ E16 expression was associated with rat hepatocarcinogenesis and human tumor cell lines; therefore, we analyzed several primary human tumors including a panel of 20 colon carcinomas to evaluate the relationship of TA1/E16… CONTINUE READING
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The gene for membrane protein E 16 ( D 16 S 49 E ) maps to human chromosome 16 q 24 . 3 andisexpressedinhumanbrain , thymusandretina

  • D. R. Maglott, A. S. Durkin, S. A. Lane, D. F. Callen, T. V. Feldblyum, W. C. Nierman
  • Genomics
  • 1994

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