Expression of a functional N-methyl-D-aspartate-type glutamate receptor by bone marrow megakaryocytes.

@article{Genever1999ExpressionOA,
  title={Expression of a functional N-methyl-D-aspartate-type glutamate receptor by bone marrow megakaryocytes.},
  author={Paul Genever and Daniel James Wilkinson and Aaron J. Patton and Nicola M Peet and Ying Hong and Anjili Mathur and Jorge D. Erusalimsky and Timothy M. Skerry},
  journal={Blood},
  year={1999},
  volume={93 9},
  pages={2876-83}
}
Better understanding of hemostasis will be possible by the identification of new lineage-specific stimuli that regulate platelet formation. We describe a novel functional megakaryocyte receptor that belongs to a family of ionotropic glutamate receptors of the N-methyl-D-aspartate (NMDA) subtype responsible for synaptic neurotransmission in the central nervous system (CNS). Northern blotting and reverse-transcriptase polymerase chain reaction (RT-PCR) studies identified expression of NMDAR1 and… CONTINUE READING
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