Expression of a cytoplasmic LINE-1 transcript is regulated in a human teratocarcinoma cell line.

@article{Skowronski1985ExpressionOA,
  title={Expression of a cytoplasmic LINE-1 transcript is regulated in a human teratocarcinoma cell line.},
  author={J. Skowronski and M. F. Singer},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1985},
  volume={82 18},
  pages={6050-4}
}
The major primate family of highly repeated, long interspersed DNA sequences (LINE-1, previously Kpn I, family) includes several thousand 6-kilobase-pair long units that terminate in an A-rich stretch. Recent evidence indicates that long open reading frames occur in at least some family members. These results suggested that one or more LINE-1 family members might be structural genes. Accordingly, a variety of human cell lines was analyzed for the presence of a cytoplasmic, polyadenylylated RNA… CONTINUE READING