Expression of a cDNA encoding Phytolacca insularis antiviral protein confers virus resistance on transgenic potato plants.

@article{Moon1997ExpressionOA,
  title={Expression of a cDNA encoding Phytolacca insularis antiviral protein confers virus resistance on transgenic potato plants.},
  author={Younghye Moon and Seong Kyu Song and Kyu Wan Choi and Jung Sup Lee},
  journal={Molecules and cells},
  year={1997},
  volume={7 6},
  pages={807-15}
}
To develop an antiviral agent and virus-resistant plants, a cDNA clone encoding Phytolacca insularis antiviral protein (PIP) was isolated from a cDNA library constructed with poly(A)+ RNA purified from leaves of P. insularis. The PIP cDNA contains an open reading frame encoding 307 amino acids. The deduced amino acid sequence includes a putative signal sequence of 22 amino acids at the N-terminus. The amino acid sequence of PIP shares 84% homology with that of the pokeweed antiviral protein… CONTINUE READING
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