Expression of a Single, Viral Oncoprotein in Skin Epithelium Is Sufficient to Recruit Lymphocytes

@inproceedings{Choyce2013ExpressionOA,
  title={Expression of a Single, Viral Oncoprotein in Skin Epithelium Is Sufficient to Recruit Lymphocytes},
  author={Allison Choyce and Michelle J. Yong and Sharmal Narayan and Stephen R. Mattarollo and Amy Liem and Paul F Lambert and Ian H Frazer and Graham R Leggatt},
  booktitle={PloS one},
  year={2013}
}
Established cancers are frequently associated with a lymphocytic infiltrate that fails to clear the tumour mass. In contrast, the importance of recruited lymphocytes during premalignancy is less well understood. In a mouse model of premalignant skin epithelium, transgenic mice that express the human papillomavirus type 16 (HPV16) E7 oncoprotein under a… CONTINUE READING