Expression of X-linked inhibitor of apoptosis as a novel prognostic marker in radically resected non-small cell lung cancer patients.

@article{Ferreira2001ExpressionOX,
  title={Expression of X-linked inhibitor of apoptosis as a novel prognostic marker in radically resected non-small cell lung cancer patients.},
  author={Carlos Gil Ferreira and Paul D. L. P. M. van der Valk and Simone W. Span and Inge Ludwig and Egbert F. Smit and Frank A. E. Kruyt and Herbert M. Pinedo and Harm van Tinteren and Guiseppe Giaccone},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2001},
  volume={7 8},
  pages={2468-74}
}
PURPOSE To assess the pattern of expression and the prognostic value of the inhibitor of apoptosis family member X-linked inhibitor of apoptosis (XIAP; MIHA/ILP-a) in radically resected non-small cell lung cancer patients. EXPERIMENTAL DESIGN The expression of XIAP and its relationship with overall survival was analyzed by immunohistochemistry on tumors from 144 patients with early-stage non-small cell lung cancer. In addition, the apoptotic and mitotic index, Ki-67, p53, and bcl-2 levels… CONTINUE READING
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