Expression of VEGF-A/C, VEGF-R2, PDGF-α/β, c-kit, EGFR, Her-2/Neu, Mcl-1 and Bmi-1 in Merkel cell carcinoma

@article{Brunner2008ExpressionOV,
  title={Expression of VEGF-A/C, VEGF-R2, PDGF-α/β, c-kit, EGFR, Her-2/Neu, Mcl-1 and Bmi-1 in Merkel cell carcinoma},
  author={Markus Brunner and Dietmar Thurnher and Johannes Pammer and Silvana Geleff and Gregor Heiduschka and Christina M. Reinisch and Peter Petzelbauer and Boban M. Erovic},
  journal={Modern Pathology},
  year={2008},
  volume={21},
  pages={876-884}
}
Merkel cell carcinoma is a rare but very aggressive tumor of the skin. With current treatment options, Merkel cell carcinoma is associated with a high incidence of recurrence and metastasis. Targeted anticancer therapies such as receptor tyrosine kinase inhibitors and antisense oligonucleotides have been found to be a promising new type of treatment for various types of cancer. To evaluate whether the use of targeted therapies is a possible treatment option in Merkel cell carcinoma, we… CONTINUE READING