Expression of Toll-like receptor 2 in duodenal biopsies from dogs with inflammatory bowel disease is associated with severity of disease.

@article{McMahon2010ExpressionOT,
  title={Expression of Toll-like receptor 2 in duodenal biopsies from dogs with inflammatory bowel disease is associated with severity of disease.},
  author={Louise A. McMahon and Arthur K House and Brian Catchpole and Jocelyn G. Elson-Riggins and A. L. Riddle and Ken Smith and Dirk Werling and Iwan A Burgener and Karin Allenspach},
  journal={Veterinary immunology and immunopathology},
  year={2010},
  volume={135 1-2},
  pages={
          158-163
        }
}
  • Louise A. McMahon, Arthur K House, +6 authors Karin Allenspach
  • Published in
    Veterinary immunology and…
    2010
  • Biology, Medicine
  • There is growing evidence that aberrant innate immune responses towards the bacterial flora of the gut play a role in the pathogenesis of canine inflammatory bowel disease (IBD). Toll-like receptors (TLR) play an important role as primary sensors of invading pathogens and have gained significant attention in human IBD as differential expression and polymorphisms of certain TLR have been shown to occur in ulcerative colitis (UC) and Crohn's disease (CD). The aim of the current study was to… CONTINUE READING

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