Expression of Toll‐like receptors in nasal epithelium in allergic rhinitis

  title={Expression of Toll‐like receptors in nasal epithelium in allergic rhinitis},
  author={Jutta A Renkonen and Sanna Toppila‐Salmi and Sakari Joenv{\"a}{\"a}r{\"a} and Pirkko Mattila and Ville I Parviainen and Jaana Hagstr{\"o}m and Caj Haglund and Mikko Lehtonen and Risto L O Renkonen},
  booktitle={APMIS : acta pathologica, microbiologica, et immunologica Scandinavica},
Toll-like receptors (TLRs) are important in barrier homeostasis, but their role in airborne allergies is not fully understood. The aim was to evaluate baseline and allergen-induced expression of TLR proteins in nasal epithelium during allergic rhinitis. Nineteen otherwise healthy non-smoking volunteers both allergic to birch pollen and non-allergic controls were enrolled. We took nasal biopsies before and after off-seasonal intranasal birch pollen or diluent challenge. The expression of… CONTINUE READING


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