Expression of TGF-beta and its receptors in murine fetal and adult dermal wounds.

@article{Cowin2001ExpressionOT,
  title={Expression of TGF-beta and its receptors in murine fetal and adult dermal wounds.},
  author={Allison June Cowin and Thomas M. Holmes and Patrick Brosnan and Mandolin W. Ferguson},
  journal={European journal of dermatology : EJD},
  year={2001},
  volume={11 5},
  pages={
          424-31
        }
}
The transforming growth factor-betas (TGF-betas) are of major importance in wound healing and have been implicated in the scar-less wound repair observed in fetuses. Few studies have characterised the role of TGF-beta in fetal wound repair and to date no studies have characterised the expression of its receptors within non-scarring fetal wounds. We have localised the TGF-beta isoforms beta1, beta2 and beta3 and its two receptors, TGF-betaRI and TGF-betaRII in both adult and fetal dermal murine… CONTINUE READING

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