Expression of TGF-βs and TGF-β type II receptor in cerebrospinal fluid of patients with idiopathic normal pressure hydrocephalus

@article{Li2007ExpressionOT,
  title={Expression of TGF-$\beta$s and TGF-$\beta$ type II receptor in cerebrospinal fluid of patients with idiopathic normal pressure hydrocephalus},
  author={Xianfeng Li and M. Miyajima and Chuanlu Jiang and H. Arai},
  journal={Neuroscience Letters},
  year={2007},
  volume={413},
  pages={141-144}
}
We investigated cerebrospinal fluid (CSF) samples from 21 patients with idiopathic normal pressure hydrocephalus (INPH) and 14 controls without neurological disease. The concentrations of leucine-rich alpha-2-glycoprotein (LRG), transforming growth factor (TGF)-beta1, 2, 3 and TGF-beta type II receptor (TbetaR-II) in CSF were measured using ELISA. TGF-beta1, TbetaR-II and LRG CSF levels of patients with INPH were significantly higher than controls, whereas no significant differences in TGF… Expand
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