Expression of TAK1, a mediator of TGF-beta and BMP signaling, during mouse embryonic development.

@article{Jadrich2003ExpressionOT,
  title={Expression of TAK1, a mediator of TGF-beta and BMP signaling, during mouse embryonic development.},
  author={Joy L Jadrich and Michael B O'connor and Electra Coucouvanis},
  journal={Gene expression patterns : GEP},
  year={2003},
  volume={3 2},
  pages={131-4}
}
TGF-beta activated kinase 1 (TAK1) is a MAP kinase kinase kinase (MAPKKK) that has been shown to function downstream of BMPs and TGF-beta (J. Biol. Chem. 275 (2000) 17647; EMBO J. 17 (1998) 1019; Science 270 (1995) 2008), as well as in the interleukin-1 (IL-1) signaling pathway (J. Biol. Chem. 276 (2001) 3508; Nature 398 (1999) 252). Using… CONTINUE READING