Expression of Stem Cell Markers in the Human Fetal Kidney

@article{Metsuyanim2009ExpressionOS,
  title={Expression of Stem Cell Markers in the Human Fetal Kidney},
  author={Sally Metsuyanim and Orit Harari‐Steinberg and Ella Buzhor and Dorit Omer and Naomi Pode-Shakked and Herzl Ben‐Hur and Reuvit Halperin and David F. Schneider and Benjamin Dekel},
  journal={PLoS ONE},
  year={2009},
  volume={4}
}
In the human fetal kidney (HFK) self-renewing stem cells residing in the metanephric mesenchyme (MM)/blastema are induced to form all cell types of the nephron till 34th week of gestation. Definition of useful markers is crucial for the identification of HFK stem cells. Because wilms' tumor, a pediatric renal cancer, initiates from retention of renal stem cells, we hypothesized that surface antigens previously up-regulated in microarrays of both HFK and blastema-enriched stem-like wilms' tumor… Expand
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