Expression of Sox2 in mouse taste buds and its relation to innervation

Abstract

Sox2, which encodes an HMG box transcription factor, is known to regulate the differentiation of progenitor cells of the tongue into taste bud cells versus keratinocytes during development. To determine the neural dependence of Sox2 expression, glossopharyngeal nerves of mice were cut bilaterally. In unoperated mice, the expression of Sox2 mRNA and protein… (More)
DOI: 10.1007/s00441-008-0600-1

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