Expression of Salmonella typhimurium rpoS and rpoS-dependent genes in the intracellular environment of eukaryotic cells.

@article{Chen1996ExpressionOS,
  title={Expression of Salmonella typhimurium rpoS and rpoS-dependent genes in the intracellular environment of eukaryotic cells.},
  author={C Y Chen and Lars Eckmann and Stephen James Libby and Ferric C Fang and Shigefumi Okamoto and Martin F. Kagnoff and Joshua Fierer and Donald G. Guiney},
  journal={Infection and immunity},
  year={1996},
  volume={64 11},
  pages={4739-43}
}
Adaptation to the intracellular environment of host cells is crucial for the pathogenesis of Salmonella infections. The alternative sigma factor RpoS is a global regulator of gene expression during starvation and stress conditions and is required for virulence in Salmonella spp. We have used lacZ reporter fusions to rpoS and rpoS-dependent genes to study rpoS regulation after entry of Salmonella typhimurium into macrophages and epithelial cells. The results demonstrate that expression of an… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

Similar Papers

Loading similar papers…